Lyophilized powderSelank
Selank (TP-7)
Selank is a synthetic heptapeptide derived from the immunomodulatory tetrapeptide tuftsin, extended with a Pro-Gly-Pro sequence that substantially increases stability against peptidase degradation. Research has examined its effects on BDNF expression in the hippocampus, monoamine turnover, and enkephalin degradation. The literature originates largely from Russian institutional research and much of the primary work requires translation.
Research applications
- BDNF and neurotrophic factor expression studies
- GABAergic and serotonergic system interaction assays
- Enkephalin degradation and peptidase inhibition research
- Anxiety-related behavioral models in rodents
Storage
Store lyophilized powder at -20°C protected from light. Reconstituted solution stable at 2-8°C for up to 30 days.
Reconstitution
Reconstitute with bacteriostatic water directed down the vial wall. Swirl gently.
Published literature
139 papers indexed on PubMed for Selank. Showing 6, reviews first.
- 01Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions
Rahman OF et al. · J Am Acad Orthop Surg Glob Res Rev · 2026
- 02Tuftsin - Properties and Analogs
Siebert A et al. · Curr Med Chem · 2017
- 03
- 04Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats
Konstantinopolsky MA et al. · Bull Exp Biol Med · 2022
- 05Long-term Survival of Adhesively Luted Post-endodontic Restorations
Bruhnke M et al. · J Endod · 2022
- 06Functional Connectomic Approach to Studying Selank and Semax Effects
Panikratova YR et al. · Dokl Biol Sci · 2020
Indexed from PubMed, 2026-07-19. We link to sources rather than reproducing them.
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Heptapeptide ACTH(4-10) analog studied for BDNF expression and neurotrophic signaling, without corticotropic activity.
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DSIP
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