Lyophilized powderThymosin Alpha-1
Thymosin Alpha-1 (Tα1)
Thymosin alpha-1 is a 28-amino-acid N-terminally acetylated peptide originally isolated from thymic tissue. It is among the better-characterized immunomodulatory peptides, with published mechanism centering on TLR2 and TLR9 signaling in dendritic cells and downstream effects on T-cell differentiation. Unlike much of this catalog, it has an established clinical literature under the name thymalfasin.
Research applications
- TLR2 and TLR9 signaling assays in dendritic cell culture
- T-cell maturation and differentiation studies
- Cytokine profiling (IL-2, IFN-γ) in immune models
- Vaccine adjuvant research
Storage
Store lyophilized at -20°C protected from light. Reconstituted at 2-8°C for up to 30 days.
Reconstitution
Reconstitute with bacteriostatic water down the vial wall. Swirl gently.
Published literature
864 papers indexed on PubMed for Thymosin Alpha-1. Showing 6, reviews first.
- 01Aging and Thymosin Alpha-1
Simonova MA et al. · Int J Mol Sci · 2025
- 02Phenotypic drug discovery: a case for thymosin alpha-1
Garaci E et al. · Front Med (Lausanne) · 2024
- 03Thymosin alpha 1: A comprehensive review of the literature
Dominari A et al. · World J Virol · 2020
- 04Thymosin alpha 1 treatment for patients with sepsis
Pei F et al. · Expert Opin Biol Ther · 2018
- 05Serum thymosin alpha 1 levels in normal and pathological conditions
Pica F et al. · Expert Opin Biol Ther · 2018
- 06Thymosin alpha 1 and HIV-1: recent advances and future perspectives
Matteucci C et al. · Future Microbiol · 2017
Indexed from PubMed, 2026-07-19. We link to sources rather than reproducing them.
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